Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-8-31
pubmed:abstractText
The recent approval of a rotavirus vaccine in Mexico motivates this study on the potential impact of the use of such a vaccine on rotavirus prevention and control. An age-structured model that describes the rotavirus transmission dynamics of infections is introduced. Conditions that guarantee the local and global stability analysis of the disease-free steady state distribution as well as the existence of an endemic steady state distribution are established. The impact of maternal antibodies on the implementation of vaccine is evaluated. Model results are used to identify optimal age-dependent vaccination strategies. A convergent numerical scheme for the model is introduced but not implemented. This paper is dedicated to Prof. K. P. Hadeler, who continues to push the frontier of knowledge in mathematical biology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0303-6812
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
719-46
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
An age-structured epidemic model of rotavirus with vaccination.
pubmed:affiliation
Department of Mathematics and Statistics, Arizona State University, P.O. Box 871804, Tempe, AZ 85287-1804, USA. alicia@mathpost.asu.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't