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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2006-10-10
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pubmed:abstractText |
In this randomized pilot clinical trial, the authors tested the hypothesis that using gabapentin as an add-on agent in the treatment of postoperative pain reduces the occurrence of postoperative delirium. Postoperative delirium occurred in 5/12 patients (42%) who received placebo vs 0/9 patients who received gabapentin, p = 0.045. The reduction in delirium appears to be secondary to the opioid-sparing effect of gabapentin.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1251-3
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16914695-Amines,
pubmed-meshheading:16914695-Analgesics,
pubmed-meshheading:16914695-Cyclohexanecarboxylic Acids,
pubmed-meshheading:16914695-Delirium,
pubmed-meshheading:16914695-Feasibility Studies,
pubmed-meshheading:16914695-Female,
pubmed-meshheading:16914695-Humans,
pubmed-meshheading:16914695-Male,
pubmed-meshheading:16914695-Middle Aged,
pubmed-meshheading:16914695-Neurosurgical Procedures,
pubmed-meshheading:16914695-Pain, Postoperative,
pubmed-meshheading:16914695-Pain Measurement,
pubmed-meshheading:16914695-Pilot Projects,
pubmed-meshheading:16914695-Placebo Effect,
pubmed-meshheading:16914695-Premedication,
pubmed-meshheading:16914695-Spine,
pubmed-meshheading:16914695-Treatment Outcome,
pubmed-meshheading:16914695-gamma-Aminobutyric Acid
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pubmed:year |
2006
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pubmed:articleTitle |
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
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pubmed:affiliation |
Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA 94143-0648, USA. leungj@anesthesia.ucsf.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, N.I.H., Extramural
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