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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1990-5-16
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pubmed:abstractText |
Five mouse hybridomas which produce monoclonal antibodies against the p17 core protein of HIV-1 have been isolated. Cross-competition assays and mapping with synthetic peptides demonstrate that two closely related epitopes are identified by these antibodies. Directed against two neighbouring peptides at the carboxy-terminal end of the molecule, they can be used for the selective detection of p17 polypeptide in a viral extract or in an infected cell lysate by a solid-phase sandwich enzyme immunoassay.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/HGP-30 peptide, Human...,
http://linkedlifedata.com/resource/pubmed/chemical/HIV Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/gag Gene Products, Human...
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0022-1759
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
17
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pubmed:volume |
128
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-75
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1691236-Amino Acid Sequence,
pubmed-meshheading:1691236-Animals,
pubmed-meshheading:1691236-Antibodies, Monoclonal,
pubmed-meshheading:1691236-Antibodies, Viral,
pubmed-meshheading:1691236-Antibody Specificity,
pubmed-meshheading:1691236-Blotting, Western,
pubmed-meshheading:1691236-Cell Line,
pubmed-meshheading:1691236-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1691236-Epitopes,
pubmed-meshheading:1691236-HIV Antigens,
pubmed-meshheading:1691236-HIV Seropositivity,
pubmed-meshheading:1691236-HIV-1,
pubmed-meshheading:1691236-Humans,
pubmed-meshheading:1691236-Mice,
pubmed-meshheading:1691236-Mice, Inbred BALB C,
pubmed-meshheading:1691236-Molecular Sequence Data,
pubmed-meshheading:1691236-Peptide Mapping,
pubmed-meshheading:1691236-Peptides,
pubmed-meshheading:1691236-Precipitin Tests,
pubmed-meshheading:1691236-gag Gene Products, Human Immunodeficiency Virus
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pubmed:year |
1990
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pubmed:articleTitle |
Characterization of monoclonal antibodies against the p17 core protein of the human immunodeficiency virus 1.
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pubmed:affiliation |
Institut Pasteur du Brabant, Brussels, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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