Source:http://linkedlifedata.com/resource/pubmed/id/16911943
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2006-8-16
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| pubmed:abstractText |
Dendritic cells (DCs) loaded with complex antigen are always used to induce cytotoxic T lymphocytes (CTLs) which have a specific anti-tumor activity. However, CTLs can assault autologous cells induced by DCs loaded with autologous antigen. This study aimed to explore how to weaken the autoimmune reaction induced by DC vaccine by combining mature DC (mDC) activating immunity and immature DC (imDC) leading to immune tolerance to make hepatocellular carcinoma (HCC) vaccine in vitro.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
1499-3872
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
422-7
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| pubmed:meshHeading |
pubmed-meshheading:16911943-Carcinoma, Hepatocellular,
pubmed-meshheading:16911943-Cell Line, Tumor,
pubmed-meshheading:16911943-Dendritic Cells,
pubmed-meshheading:16911943-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16911943-Flow Cytometry,
pubmed-meshheading:16911943-Humans,
pubmed-meshheading:16911943-T-Lymphocytes, Cytotoxic
|
| pubmed:year |
2006
|
| pubmed:articleTitle |
Effects of cytotoxic T lymphocytes on hepatoma cell line SMMC-7721 induced by different subsets of dendritic cells in vitro.
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| pubmed:affiliation |
Department of Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. wjiaxiang@zzu.edu.cn
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| pubmed:publicationType |
Journal Article,
In Vitro
|