Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-5-11
pubmed:abstractText
A neuroanatomical central nervous system (CNS) mechanism for the expression of emotions and behaviors in animals has now been proposed for over 50 years. More specifically, alterations in CNS serotonin associated with aggressive behavior in certain animal models have been among the most frequent, reliable, and replicable findings. Because alterations in CNS monoamines, i.e., catechols and indols, have been related to hypotheses for affective disorders and associated with both suicidal and aggressive behaviors, human clinical implications have emerged. The original studies, which reported an association between low cerebrospinal fluid 5-hydroxyindole-acetic acid concentration and impulsive, destructive behaviors, particularly where aggression and violence are involved, have now been replicated rather consistently in a number of countries and cultures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0160-6689
pubmed:author
pubmed:issnType
Print
pubmed:volume
51 Suppl
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-41; discussion 42-3
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
CSF serotonin metabolite (5-HIAA) studies in depression, impulsivity, and violence.
pubmed:affiliation
Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Md 20892.
pubmed:publicationType
Journal Article, Review