Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 1
pubmed:dateCreated
1990-5-16
pubmed:abstractText
Thirty-three consecutive liver-transplant recipients were prospectively studied over a 37-mo period for evidence of cytomegalovirus infection. Sixteen (48%) episodes of cytomegalovirus infection were identified; 9 were primary infections and 7 were recurrent infections. Beginning with patient 8, gamma-globulin prophylaxis was routinely administered to most patients. Twelve potential risk factors for cytomegalovirus infection were evaluated and included pretransplant cytomegalovirus serological status of donor and recipient; recipient's age, sex, race, and liver disease; number and type of blood products transfused; type and intensity of immunosuppression; and occurrence of rejection. The Cox proportional hazards model identified positive donor cytomegalovirus serology as the single most important risk factor for subsequent development of cytomegalovirus infection, regardless of recipient cytomegalovirus serological status. In addition, use of gamma-globulin prophylaxis seemed to be protective against the occurrence of disseminated cytomegalovirus disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1326-32
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed-meshheading:1691121-Adolescent, pubmed-meshheading:1691121-Adult, pubmed-meshheading:1691121-Antibodies, Viral, pubmed-meshheading:1691121-Child, pubmed-meshheading:1691121-Child, Preschool, pubmed-meshheading:1691121-Cytomegalovirus, pubmed-meshheading:1691121-Cytomegalovirus Infections, pubmed-meshheading:1691121-Follow-Up Studies, pubmed-meshheading:1691121-Humans, pubmed-meshheading:1691121-Immunosuppression, pubmed-meshheading:1691121-Incidence, pubmed-meshheading:1691121-Infant, pubmed-meshheading:1691121-Liver Transplantation, pubmed-meshheading:1691121-Middle Aged, pubmed-meshheading:1691121-Multivariate Analysis, pubmed-meshheading:1691121-Ohio, pubmed-meshheading:1691121-Postoperative Complications, pubmed-meshheading:1691121-Prospective Studies, pubmed-meshheading:1691121-Risk Factors, pubmed-meshheading:1691121-gamma-Globulins
pubmed:year
1990
pubmed:articleTitle
A multivariate analysis of risk factors for cytomegalovirus infection in liver-transplant recipients.
pubmed:affiliation
Department of Infectious Disease, Cleveland Clinic Foundation, Ohio.
pubmed:publicationType
Journal Article