| pubmed-article:16909391 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16909391 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:16909391 | lifeskim:mentions | umls-concept:C0002045 | lld:lifeskim |
| pubmed-article:16909391 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:16909391 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:16909391 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:16909391 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:16909391 | pubmed:dateCreated | 2006-8-15 | lld:pubmed |
| pubmed-article:16909391 | pubmed:abstractText | A significant proportion of the variation between individuals in gene expression levels is genetic, and it is likely that these differences correlate with phenotypic differences or with risk of disease. Cis-acting polymorphisms are important in determining interindividual differences in gene expression that lead to allelic expression imbalance, which is the unequal expression of homologous alleles in individuals heterozygous for such a polymorphism. This expression imbalance can be detected using a transcribed polymorphism, and, once it is established, the next step is to identify the polymorphisms that are responsible for or predictive of allelic expression levels. We present an expectation-maximization algorithm for such analyses, providing a formal statistical framework to test whether a candidate polymorphism is associated with allelic expression differences. | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16909391 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16909391 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16909391 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16909391 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16909391 | pubmed:issn | 0002-9297 | lld:pubmed |
| pubmed-article:16909391 | pubmed:author | pubmed-author:HeighwayJJ | lld:pubmed |
| pubmed-article:16909391 | pubmed:author | pubmed-author:TeareM DMD | lld:pubmed |
| pubmed-article:16909391 | pubmed:author | pubmed-author:Santibáñez... | lld:pubmed |
| pubmed-article:16909391 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16909391 | pubmed:volume | 79 | lld:pubmed |
| pubmed-article:16909391 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16909391 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16909391 | pubmed:pagination | 539-43 | lld:pubmed |
| pubmed-article:16909391 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:16909391 | pubmed:meshHeading | pubmed-meshheading:16909391... | lld:pubmed |
| pubmed-article:16909391 | pubmed:meshHeading | pubmed-meshheading:16909391... | lld:pubmed |
| pubmed-article:16909391 | pubmed:meshHeading | pubmed-meshheading:16909391... | lld:pubmed |
| pubmed-article:16909391 | pubmed:meshHeading | pubmed-meshheading:16909391... | lld:pubmed |
| pubmed-article:16909391 | pubmed:meshHeading | pubmed-meshheading:16909391... | lld:pubmed |
| pubmed-article:16909391 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16909391 | pubmed:articleTitle | An expectation-maximization algorithm for the analysis of allelic expression imbalance. | lld:pubmed |
| pubmed-article:16909391 | pubmed:affiliation | Division of Genomic Medicine, University of Sheffield, United Kingdom. | lld:pubmed |
| pubmed-article:16909391 | pubmed:publicationType | Journal Article | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16909391 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16909391 | lld:pubmed |
