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rdf:type |
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lifeskim:mentions |
umls-concept:C0021289,
umls-concept:C0024487,
umls-concept:C0033727,
umls-concept:C0035028,
umls-concept:C0040223,
umls-concept:C0086045,
umls-concept:C0175677,
umls-concept:C0178795,
umls-concept:C0205344,
umls-concept:C0228174,
umls-concept:C0456603,
umls-concept:C0870883
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pubmed:issue |
7
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pubmed:dateCreated |
2006-8-15
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|
pubmed:abstractText |
Results from cerebral proton (1)H-MR spectroscopy studies of neonates with perinatal hypoxic-ischemic injury have generally been presented as metabolite peak-area ratios, which are T1- and T2-weighted, rather than absolute metabolite concentrations. We hypothesized that compared with (1)H-MR spectroscopy peak-area ratios, calculation of absolute metabolite concentrations and relaxation times measured within the first 4 days after birth (1) would improve prognostic accuracy and (2) enhance the understanding of underlying neurochemical changes in neonates with neonatal encephalopathy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0195-6108
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1546-54
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pubmed:dateRevised |
2008-2-14
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pubmed:meshHeading |
pubmed-meshheading:16908578-Aspartic Acid,
pubmed-meshheading:16908578-Birth Injuries,
pubmed-meshheading:16908578-Body Water,
pubmed-meshheading:16908578-Brain,
pubmed-meshheading:16908578-Brain Chemistry,
pubmed-meshheading:16908578-Child Development,
pubmed-meshheading:16908578-Choline,
pubmed-meshheading:16908578-Creatine,
pubmed-meshheading:16908578-Follow-Up Studies,
pubmed-meshheading:16908578-Gestational Age,
pubmed-meshheading:16908578-Humans,
pubmed-meshheading:16908578-Hydrogen,
pubmed-meshheading:16908578-Hypoxia-Ischemia, Brain,
pubmed-meshheading:16908578-Infant, Newborn,
pubmed-meshheading:16908578-Lactic Acid,
pubmed-meshheading:16908578-Magnetic Resonance Spectroscopy,
pubmed-meshheading:16908578-Phosphocreatine,
pubmed-meshheading:16908578-Prognosis,
pubmed-meshheading:16908578-Protons,
pubmed-meshheading:16908578-Thalamus
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pubmed:year |
2006
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pubmed:articleTitle |
Proton MR spectroscopy in neonates with perinatal cerebral hypoxic-ischemic injury: metabolite peak-area ratios, relaxation times, and absolute concentrations.
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pubmed:affiliation |
Department of Paediatrics and Child Health, University College London, 86-96 Chenies Mews, London WC1E 6HX, UK.
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pubmed:publicationType |
Journal Article,
Comparative Study
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