rdf:type |
|
lifeskim:mentions |
umls-concept:C0003320,
umls-concept:C0007634,
umls-concept:C0017262,
umls-concept:C0023516,
umls-concept:C0185117,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C1512505,
umls-concept:C1552599,
umls-concept:C1704787,
umls-concept:C2911684
|
pubmed:issue |
2
|
pubmed:dateCreated |
1990-5-4
|
pubmed:abstractText |
Certain expression regularities of different markers in human breast cancer cells are demonstrated. Monomorphic determinants of HLA class II antigen are detected only in case of HLA class I expression and cancer-embryonal antigen (CEA); the latter is combined with HLA class I and ICO-84 antigens at a significantly higher rate. The expression effect of CEA and HLA-DR on the metastatic spreading rate of regional lymph nodes is marked. A heterogeneity of the single tumour and in patients with malignant breast cancer is determined by the presence of the "leucocytic" antigens and CEA. In parallel studies monoclonal antibodies (MAB) HMFG-1 and a common epithelial antigen are assayed. The antigen interacting with MAB HEA-125 is characterized by the monomorphic expression.
|
pubmed:language |
rus
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0204-3564
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
54-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1690634-Adult,
pubmed-meshheading:1690634-Aged,
pubmed-meshheading:1690634-Antibodies, Monoclonal,
pubmed-meshheading:1690634-Antigens, Neoplasm,
pubmed-meshheading:1690634-Breast Neoplasms,
pubmed-meshheading:1690634-Carcinoembryonic Antigen,
pubmed-meshheading:1690634-Carcinoma, Intraductal, Noninfiltrating,
pubmed-meshheading:1690634-Epitopes,
pubmed-meshheading:1690634-Female,
pubmed-meshheading:1690634-HLA Antigens,
pubmed-meshheading:1690634-Humans,
pubmed-meshheading:1690634-Leukocytes,
pubmed-meshheading:1690634-Lymphatic Metastasis,
pubmed-meshheading:1690634-Middle Aged,
pubmed-meshheading:1690634-Neoplasm Staging,
pubmed-meshheading:1690634-Phenotype,
pubmed-meshheading:1690634-Tumor Markers, Biological
|
pubmed:year |
1990
|
pubmed:articleTitle |
[The expression of leukocytic and related antigens on the cells of human breast cancer cells].
|
pubmed:publicationType |
Journal Article,
English Abstract
|