16904983

Source:http://linkedlifedata.com/resource/pubmed/id/16904983

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002199, umls-concept:C0442796, umls-concept:C0914671, umls-concept:C1280500
pubmed:issue	2
pubmed:dateCreated	2006-8-14
pubmed:abstractText	We hypothesized that interferon alpha (IFN-alpha) and unmethylated cytosine-phosphothioate-guanine (CpG)-rich oligodexoynucleotides (CpG ODNs) would elicit potent antitumor activity due to the ability of this treatment combination to activate complimentary signal transduction intermediates.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/CA93670, http://linkedlifedata.com/resource/pubmed/grant/P01-CA95426, http://linkedlifedata.com/resource/pubmed/grant/P30-CA16058
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0417347
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Adjuvants, Immunologic, http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/CPG-oligonucleotide, http://linkedlifedata.com/resource/pubmed/chemical/Cytokines, http://linkedlifedata.com/resource/pubmed/chemical/ISG15 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Interferon-alpha, http://linkedlifedata.com/resource/pubmed/chemical/Oligodeoxyribonucleotides, http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins, http://linkedlifedata.com/resource/pubmed/chemical/STAT1 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/STAT1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Ubiquitins, http://linkedlifedata.com/resource/pubmed/chemical/interferon alfa-2b
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	0039-6060
pubmed:author	pubmed-author:BrownLloydL, pubmed-author:CarsonWilliam EWE, pubmed-author:ChaudhuryAbhik RayAR, pubmed-author:CrespinTimT, pubmed-author:LesinskiGregory BGB, pubmed-author:RodaJulieJ, pubmed-author:TerrellCatherineC
pubmed:issnType	Print
pubmed:volume	140
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	297-306
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:16904983-Adjuvants, Immunologic, pubmed-meshheading:16904983-Animals, pubmed-meshheading:16904983-Antineoplastic Agents, pubmed-meshheading:16904983-Cell Culture Techniques, pubmed-meshheading:16904983-Cell Line, Tumor, pubmed-meshheading:16904983-Cytokines, pubmed-meshheading:16904983-Female, pubmed-meshheading:16904983-Humans, pubmed-meshheading:16904983-Interferon-alpha, pubmed-meshheading:16904983-Leukocytes, Mononuclear, pubmed-meshheading:16904983-Melanoma, pubmed-meshheading:16904983-Mice, pubmed-meshheading:16904983-Mice, Inbred C57BL, pubmed-meshheading:16904983-Oligodeoxyribonucleotides, pubmed-meshheading:16904983-Recombinant Proteins, pubmed-meshheading:16904983-STAT1 Transcription Factor, pubmed-meshheading:16904983-Signal Transduction, pubmed-meshheading:16904983-Ubiquitins
pubmed:year	2006
pubmed:articleTitle	Interferon alpha and CPG oligodeoxynucleotides elicit additive immunostimulatory and antitumor effects.
pubmed:affiliation	Department of Surgery, Human Cancer Genetics Program, Columbus, OH, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural