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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2006-8-10
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pubmed:abstractText |
Survival rates for squamous cell carcinoma of the head and neck (SCCHN) have remained unchanged for several decades due to local tumor recurrences as well as regional and distant metastases. Recent evidence has shown that RhoC GTPase is overexpressed in stages III and IV regionally metastatic SCCHN compared with stages I and II localized disease. This study evaluated the expression of RhoC in head and neck carcinoma and investigated the prognostic use of this marker on a large cohort of previously untreated patients with SCCHN.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4485-90
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:16899593-Blotting, Western,
pubmed-meshheading:16899593-Carcinoma, Squamous Cell,
pubmed-meshheading:16899593-Cell Line, Tumor,
pubmed-meshheading:16899593-Cohort Studies,
pubmed-meshheading:16899593-Epithelial Cells,
pubmed-meshheading:16899593-Head and Neck Neoplasms,
pubmed-meshheading:16899593-Humans,
pubmed-meshheading:16899593-Immunohistochemistry,
pubmed-meshheading:16899593-Lymphatic Metastasis,
pubmed-meshheading:16899593-Neoplasm Staging,
pubmed-meshheading:16899593-Tissue Array Analysis,
pubmed-meshheading:16899593-Tumor Markers, Biological,
pubmed-meshheading:16899593-rho GTP-Binding Proteins
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pubmed:year |
2006
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pubmed:articleTitle |
RhoC GTPase expression as a potential marker of lymph node metastasis in squamous cell carcinomas of the head and neck.
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pubmed:affiliation |
Department of Pathology, University of Michigan, Ann Arbor, 48109, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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