|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2006-9-13
|
|
pubmed:abstractText |
Matrix metalloproteinase-1 and -3 (MMP-1, MMP-3) represent proteinases that degrade macromolecules of the extracellular matrix. These enzymes play a fundamental role during destruction of periodontal tissues. Genetic polymorphisms were characterized in the promoter region of the MMP-1 and MMP-3 genes. The aim of this study was to investigate the relationship between these genetic variations with chronic periodontitis in a Brazilian population.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
D
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0303-6979
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
33
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
699-703
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:16899023-Adenine,
pubmed-meshheading:16899023-Adult,
pubmed-meshheading:16899023-Alleles,
pubmed-meshheading:16899023-Brazil,
pubmed-meshheading:16899023-Chronic Disease,
pubmed-meshheading:16899023-Female,
pubmed-meshheading:16899023-Gene Frequency,
pubmed-meshheading:16899023-Genetic Predisposition to Disease,
pubmed-meshheading:16899023-Genetic Variation,
pubmed-meshheading:16899023-Genotype,
pubmed-meshheading:16899023-Guanine,
pubmed-meshheading:16899023-Haplotypes,
pubmed-meshheading:16899023-Humans,
pubmed-meshheading:16899023-Male,
pubmed-meshheading:16899023-Matrix Metalloproteinase 1,
pubmed-meshheading:16899023-Matrix Metalloproteinase 3,
pubmed-meshheading:16899023-Periodontal Attachment Loss,
pubmed-meshheading:16899023-Periodontitis,
pubmed-meshheading:16899023-Polymerase Chain Reaction,
pubmed-meshheading:16899023-Polymorphism, Genetic,
pubmed-meshheading:16899023-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:16899023-Promoter Regions, Genetic
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population.
|
|
pubmed:affiliation |
Oral Biology Program, University of Sagrado, Coração-Bauru, SP, Brazil.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
