Linked Life Data

1689814

Source:http://linkedlifedata.com/resource/pubmed/id/1689814

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-4-6
pubmed:abstractText
HLHS is a complex developmental malformation of the left ventricle, aorta, and associated valves. Survival beyond neonatal life is the exception in untreated infants. The prognosis, however, is no longer hopeless. Newer surgical strategies of staged palliative reconstruction and heart replacement by transplantation appear promising. These options on occasion will become complementary in the management of individual patients. Those children surviving Fontan operations are frequently able to lead NYHA Class I or II lives without drugs, while transplant recipients will require one or more immunoregulative medications indefinitely. Exercise tolerance and work capacity following the Fontan procedure are reported to be 40 to 60 per cent of expected normals. Full functional capacity of successfully palliated children may never be normal. In contrast, exercise capability after heart transplantation is generally better than that following a Fontan operation, with cardiac ejection fractions approaching normal for age. Durability of these new management technologies will make inappropriate the traditional "do nothing" approach to HLHS in all but a few cases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0031-3955
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
137-50
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Hypoplastic left heart syndrome.
pubmed:affiliation
Department of Surgery, Loma Linda University Medical Center, California.
pubmed:publicationType
Journal Article, Review