rdf:type |
|
lifeskim:mentions |
|
pubmed:dateCreated |
2006-8-10
|
pubmed:abstractText |
We have reported a remarkably high anti-tumor efficacy using intra arterial 5-FU infusion chemotherapy combined with subcutaneous interferon-alpha injection to treat advanced hepatocellular carcinoma (HCC) with portal vein thrombus. However, we have been confirming distant metastases along with a prognosis extension as hepatic lesions could possibly be controlled to a certain extent. Even though there has been no effective chemotherapy against hepatocellular carcinoma with distant metastases, we performed S-1 and interferon-alpha combination chemotherapy for the cases where good results were exhibited from interferon-alpha combined with arterial 5-FU infusion. As a result, we confirmed CR in the anti-tumor effect against distant metastases with no severe adverse effects. It was suggested that a combination therapy of S-1 and interferon-alpha may be one of the most effective treatment modalities against advanced HCC with distant metastases.
|
pubmed:language |
jpn
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0385-0684
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
33 Suppl 1
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
230-5
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:16898008-Administration, Oral,
pubmed-meshheading:16898008-Aged,
pubmed-meshheading:16898008-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16898008-Carcinoma, Hepatocellular,
pubmed-meshheading:16898008-Drug Administration Schedule,
pubmed-meshheading:16898008-Drug Combinations,
pubmed-meshheading:16898008-Humans,
pubmed-meshheading:16898008-Interferon-alpha,
pubmed-meshheading:16898008-Liver Neoplasms,
pubmed-meshheading:16898008-Middle Aged,
pubmed-meshheading:16898008-Neoplastic Cells, Circulating,
pubmed-meshheading:16898008-Oxonic Acid,
pubmed-meshheading:16898008-Remission Induction,
pubmed-meshheading:16898008-Tegafur
|
pubmed:year |
2006
|
pubmed:articleTitle |
[S-1 treatment against advanced HCC].
|
pubmed:affiliation |
Dept. of Surgery, Osaka University, Graduate School of Medicine, Japan.
|
pubmed:publicationType |
Journal Article,
English Abstract
|