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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-8-23
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pubmed:abstractText |
Atomoxetine is a potent and selective norepinephrine transporter (NET) reuptake inhibitor acting as a nonstimulant for the treatment of attention-deficit/hyperactivity disorder (ADHD). Previous positron emission tomography (PET) studies had failed to demonstrate the feasibility of measuring a dose-dependent and saturable NET occupancy in human brain using [11C]MeNER.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0033-3158
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pubmed:author |
pubmed-author:AiraksinenAnuA,
pubmed-author:FardeLarsL,
pubmed-author:GulyásBalázsB,
pubmed-author:HalldinChristerC,
pubmed-author:InnisRobert BRB,
pubmed-author:KielbasaWilliamW,
pubmed-author:SchouMagnusM,
pubmed-author:SenecaNicholasN,
pubmed-author:TauscherJohannesJ,
pubmed-author:VandenhendeFrancoisF,
pubmed-author:VarroneAndreaA
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pubmed:issnType |
Print
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pubmed:volume |
188
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
119-27
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pubmed:meshHeading |
pubmed-meshheading:16896954-Adrenergic Uptake Inhibitors,
pubmed-meshheading:16896954-Animals,
pubmed-meshheading:16896954-Binding, Competitive,
pubmed-meshheading:16896954-Brain,
pubmed-meshheading:16896954-Dose-Response Relationship, Drug,
pubmed-meshheading:16896954-Fluorine Radioisotopes,
pubmed-meshheading:16896954-Macaca fascicularis,
pubmed-meshheading:16896954-Morpholines,
pubmed-meshheading:16896954-Norepinephrine Plasma Membrane Transport Proteins,
pubmed-meshheading:16896954-Positron-Emission Tomography,
pubmed-meshheading:16896954-Propylamines,
pubmed-meshheading:16896954-Protein Binding
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pubmed:year |
2006
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pubmed:articleTitle |
Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2.
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pubmed:affiliation |
Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska Hospital, S-17176, Stockholm, Sweden. Nicholasseneca@mail.nih.gov
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Intramural
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