Source:http://linkedlifedata.com/resource/pubmed/id/16896822
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2006-8-15
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pubmed:abstractText |
In the study presented here, data collected prospectively from 340 adult patients hospitalised in five countries with bacteremic pneumococcal CAP and treated with a ss-lactam +/- a macrolide were analysed retrospectively to evaluate the efficacy of this antimicrobial combination. Univariate and multivariate analyses revealed no significant effect on case fatality rate when a macrolide/ss-lactam regimen was used as initial therapy. Results were not affected by severity of illness, or by excluding patients who died within 2 days of admission. Identified predictors of death in a multivariate regression model were age >65 years (OR=2.6), two or more lung lobes affected (OR=2.2), and severity of disease as estimated using the acute physiology score (APS)>8.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0934-9723
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
518-21
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pubmed:meshHeading |
pubmed-meshheading:16896822-Adult,
pubmed-meshheading:16896822-Anti-Bacterial Agents,
pubmed-meshheading:16896822-Bacteremia,
pubmed-meshheading:16896822-Drug Therapy, Combination,
pubmed-meshheading:16896822-Female,
pubmed-meshheading:16896822-Humans,
pubmed-meshheading:16896822-Lactams,
pubmed-meshheading:16896822-Macrolides,
pubmed-meshheading:16896822-Male,
pubmed-meshheading:16896822-Pneumonia, Pneumococcal,
pubmed-meshheading:16896822-Prospective Studies,
pubmed-meshheading:16896822-Streptococcus pneumoniae,
pubmed-meshheading:16896822-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Addition of a macrolide to a ss-lactam in bacteremic pneumococcal pneumonia.
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pubmed:affiliation |
Department of Medicine, Infectious Disease Unit, Karolinska University Hospital, 14186 Stockholm, Sweden. richard.dwyer@karolinska.se
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pubmed:publicationType |
Journal Article
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