rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2006-8-9
|
pubmed:abstractText |
For many decades, it has been speculated that sex hormones play a role in systemic lupus erythematosus. Recent data accumulated during the past few years provide striking evidence that hormonal modulation of B cells can have a profound impact on the survival, maturation and repertoire selection of autoreactive B cells and begin to explain the sex bias associated with the condition.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1040-8711
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
456-61
|
pubmed:meshHeading |
pubmed-meshheading:16896282-Animals,
pubmed-meshheading:16896282-Antibodies, Antinuclear,
pubmed-meshheading:16896282-B-Lymphocytes,
pubmed-meshheading:16896282-Cell Survival,
pubmed-meshheading:16896282-Estrogens,
pubmed-meshheading:16896282-Female,
pubmed-meshheading:16896282-Humans,
pubmed-meshheading:16896282-Lupus Erythematosus, Systemic,
pubmed-meshheading:16896282-Lymphocyte Activation,
pubmed-meshheading:16896282-Male,
pubmed-meshheading:16896282-Mice,
pubmed-meshheading:16896282-Mice, Transgenic,
pubmed-meshheading:16896282-Prolactin,
pubmed-meshheading:16896282-Self Tolerance,
pubmed-meshheading:16896282-Sex Characteristics,
pubmed-meshheading:16896282-Signal Transduction,
pubmed-meshheading:16896282-T-Lymphocytes
|
pubmed:year |
2006
|
pubmed:articleTitle |
Sex and systemic lupus erythematosus: the role of the sex hormones estrogen and prolactin on the regulation of autoreactive B cells.
|
pubmed:affiliation |
Department of Medicine, Columbia University, 1130 St. Nicholas Avenue, New York, NY 10032, USA.
|
pubmed:publicationType |
Journal Article,
Review
|