Linked Life Data

1689474

Source:http://linkedlifedata.com/resource/pubmed/id/1689474

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1990-3-19
pubmed:abstractText
Bipolar concentric stimulating electrodes were placed medially within the nucleus raphe magnus and laterally within the nucleus gigantocellularis. The levels of norepinephrine (NE), serotonin (5-HT), and 5-hydroxyindolacetic acid (5-HIAA) within the dorsal horn of the spinal cord were measured before and after electrical stimulation of these brainstem nuclei using in vivo dialysis coupled with high pressure liquid chromatography and electrochemical detection. Stimulation medially significantly increased the levels of all three amines. While simulation laterally also increased NE, both 5-HT and 5-HIAA were significantly reduced. The relevance of these findings to descending modulation of ascending nociceptive neural activity within the dorsal horn is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
108
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
231-6
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Descending modulation of dorsal horn biogenic amines as determined by in vivo dialysis.
pubmed:affiliation
Department of Biology, California State University at Fresno 93740-0073.
pubmed:publicationType
Journal Article