16894115

Source:http://linkedlifedata.com/resource/pubmed/id/16894115

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0012929, umls-concept:C0162670, umls-concept:C0205329, umls-concept:C0333668
pubmed:issue	3
pubmed:dateCreated	2006-8-8
pubmed:abstractText	The authors studied seven patients with mitochondrial DNA (mtDNA) myopathy. Over time, there was a progressive depletion of mtDNA, which preferentially affected wild-type mitochondrial genomes. This suggests that loss of wild-type mtDNA is a major feature of mtDNA myopathy, and preventing wild-type mtDNA depletion has treatment implications.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/074454
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0401060
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/DNA, Mitochondrial
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1526-632X
pubmed:author	pubmed-author:BrownDenise TDT, pubmed-author:ChinneryPatrick FPF, pubmed-author:DurhamSteve ESE, pubmed-author:TurnbullDouglass MDM
pubmed:issnType	Electronic
pubmed:day	8
pubmed:volume	67
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	502-4
pubmed:dateRevised	2011-1-5
pubmed:meshHeading	pubmed-meshheading:16894115-DNA, Mitochondrial, pubmed-meshheading:16894115-Female, pubmed-meshheading:16894115-Follow-Up Studies, pubmed-meshheading:16894115-Gene Deletion, pubmed-meshheading:16894115-Humans, pubmed-meshheading:16894115-Male, pubmed-meshheading:16894115-Mitochondrial Myopathies
pubmed:year	2006
pubmed:articleTitle	Progressive depletion of mtDNA in mitochondrial myopathy.
pubmed:affiliation	Mitochondrial Research Group, Neurology, University of Newcastle upon Tyne, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't