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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2006-9-27
pubmed:abstractText
Fifty-six different Chinese medicinal herbs from 29 families were evaluated for their antiviral activities against duck hepatitis B virus (DHBV) in vitro. The DHBV DNA level in primary duck hepatocyte cultures was monitored by dot blot hybridization and the cytotoxicity was evaluated by MTT assay. Anti-DHBV activities were found more strongly in the aqueous extracts of Ardisia chinensis and Pithecellobium clypearia with selective indices of 2.6 and >2.7, respectively, which were comparable to that of 2',3'-dideoxycytidine. Further research on the isolation of the active antiviral phytochemicals from these herbs may provide alternative options for the treatment of chronic hepatitis B.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0951-418X
pubmed:author
pubmed:copyrightInfo
Copyright 2006 John Wiley & Sons, Ltd.
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
911-4
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
In vitro antiviral activities of Chinese medicinal herbs against duck hepatitis B virus.
pubmed:affiliation
Natural Product and TCM Pharmacology Research Laboratory, Department of Biology, The Chinese University of Hong Kong, Shatin, N. T., Hong Kong, People's Republic of China.
pubmed:publicationType
Journal Article