Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2006-9-4
pubmed:abstractText
The experience with direct myocardial injection of adenovirus encoding angiogenic growth factor is limited to invasive surgical approach. Accordingly, we sought to evaluate, for the first time, in a randomized, double-blind, placebo-controlled, phase I pilot study the safety and feasibility of percutaneous catheter-based intramyocardial delivery of a replication-deficient adenovector encoding the 121-amino-acid isoform of vascular endothelial growth factor (AdVEGF121).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1522-1946
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
372-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:16892433-Adult, pubmed-meshheading:16892433-Aged, pubmed-meshheading:16892433-Aged, 80 and over, pubmed-meshheading:16892433-Analysis of Variance, pubmed-meshheading:16892433-Angina Pectoris, pubmed-meshheading:16892433-Angiogenesis Inducing Agents, pubmed-meshheading:16892433-Biological Markers, pubmed-meshheading:16892433-Coronary Artery Disease, pubmed-meshheading:16892433-Creatine Kinase, MB Form, pubmed-meshheading:16892433-Double-Blind Method, pubmed-meshheading:16892433-Exercise Tolerance, pubmed-meshheading:16892433-Feasibility Studies, pubmed-meshheading:16892433-Female, pubmed-meshheading:16892433-Follow-Up Studies, pubmed-meshheading:16892433-Heart Catheterization, pubmed-meshheading:16892433-Humans, pubmed-meshheading:16892433-Injections, pubmed-meshheading:16892433-Male, pubmed-meshheading:16892433-Middle Aged, pubmed-meshheading:16892433-Myocardium, pubmed-meshheading:16892433-Physical Endurance, pubmed-meshheading:16892433-Pilot Projects, pubmed-meshheading:16892433-Quality of Life, pubmed-meshheading:16892433-Time Factors, pubmed-meshheading:16892433-Treatment Outcome, pubmed-meshheading:16892433-Troponin T, pubmed-meshheading:16892433-Vascular Endothelial Growth Factor A
pubmed:year
2006
pubmed:articleTitle
A randomized, double-blind, placebo-controlled, multicenter, pilot study of the safety and feasibility of catheter-based intramyocardial injection of AdVEGF121 in patients with refractory advanced coronary artery disease.
pubmed:affiliation
Cardiology Department, Rabin Medical Center, Petach-Tikva, Israel. shmuelf@clalit.org.il
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Multicenter Study, Clinical Trial, Phase I