Linked Life Data

16890417

Source:http://linkedlifedata.com/resource/pubmed/id/16890417

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-2-9
pubmed:abstractText
Impaired skeletal muscle function has been reported in patients with chronic obstructive disease (COPD), but such impairment is not homogenous and its distribution between the upper and the lower limbs is still unclear. The present study was designed to assess and compare upper and lower limb capacities in patients with moderate to severe COPD during incremental and constant-load exercises. Thirteen COPD patients of similar age with moderate to severe air flow limitation (FEV(1): 35%+/-5% predicted) and 19 healthy subjects were studied. Four sessions were organized: two incremental and two constant-load cycling exercises with arm or leg in randomized order. As observed in a previous study involving incremental and constant tests, power, VO(2), RER, VE, and HR were all significantly lower in the upper and lower limbs of patients with COPD than in healthy controls. In the healthy population, aerobic capacity and mechanical efficiency (ME) were lower in the course of arm exercises than in leg exercises. For the same relative workload, dyspnea and blood lactate production were higher during arm exercise. In contrast, no significant difference was observed between arm and leg capacities for any of these parameters in COPD patients. Conclusion: Although aerobic capacity is impaired in COPD patients, arm aerobic capacity is relatively preserved. Given the lack of significant difference between arm and leg capacities in COPD, we hypothesize that upper limb muscles are less compromised than lower limb muscles in this patient population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0954-6111
pubmed:author
pubmed:issnType
Print
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
547-53
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Is impairment similar between arm and leg cranking exercise in COPD patients?
pubmed:affiliation
IMNSSA, B.P.610-83800 Toulon Armées, France. olivier.astagna@wanadoo.fr
pubmed:publicationType
Journal Article, Randomized Controlled Trial