Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-8-4
pubmed:abstractText
The glucagon-like peptides, GLP-1 and GLP-2, are cosecreted by intestinal L cells in response to nutrient ingestion. These peptides exert multiple effects on the gastrointestinal tract and pancreas to regulate the digestion, absorption, and assimilation of ingested nutrients, as well as providing feedback signals to the brain to modulate food intake. Tropic effects of GLP-1 and GLP-2 on their major peripheral target tissues, the beta cell and the intestinal epithelium, respectively, further enhance capacity for nutrient handling. When taken together, these findings demonstrate the diverse actions of the intestinal glucagon-like peptides to regulate nutrient homeostasis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0077-8923
pubmed:author
pubmed:issnType
Print
pubmed:volume
1070
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
10-26
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
The glucagon-like peptides: pleiotropic regulators of nutrient homeostasis.
pubmed:affiliation
Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8 Canada. p.brubaker@utoronto.ca
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't