Source:http://linkedlifedata.com/resource/pubmed/id/16886608
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4B
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pubmed:dateCreated |
2006-8-4
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pubmed:abstractText |
Methylenetetrahydrofolate reductase plays a central role in converting folate to methyl donor for DNA methylation. Recently, methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) mutations were discovered to be associated with childhood acute lymphoblastic leukemia (ALL), as well as colon cancer, lymphoma, esophageal and stomach cancer. Therefore, it was hypothesized that the MTHFR polymorphisms are associated with the risk of childhood ALL in the Korean population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2879-81
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16886608-Adolescent,
pubmed-meshheading:16886608-Child,
pubmed-meshheading:16886608-Child, Preschool,
pubmed-meshheading:16886608-DNA, Neoplasm,
pubmed-meshheading:16886608-Female,
pubmed-meshheading:16886608-Genotype,
pubmed-meshheading:16886608-Humans,
pubmed-meshheading:16886608-Infant,
pubmed-meshheading:16886608-Korea,
pubmed-meshheading:16886608-Male,
pubmed-meshheading:16886608-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:16886608-Mutation,
pubmed-meshheading:16886608-Polymorphism, Genetic,
pubmed-meshheading:16886608-Precursor Cell Lymphoblastic Leukemia-Lymphoma
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pubmed:articleTitle |
Association of the methylenetetrahydrofolate reductase polymorphism in Korean patients with childhood acute lymphoblastic leukemia.
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pubmed:affiliation |
Institute for Clinical Research, Bundang CHA General Hospital, College of Medicine, Pochon CHA University, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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