rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2006-8-3
|
pubmed:abstractText |
Three new members of the fluostatin family, fluostatins C-E, were discovered in a culture filtrate extract of strain Acta 1383 during an HPLC screening program. The producing strain belongs to the genus Streptomyces and is closely related to type strains classified in the Streptomyces lavendulae 16S rRNA subclade. Fluostatins are named by their characteristic fluorenone chromophore. Fluostatin C shows moderate activity against selected human tumor cell lines.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0021-8820
|
pubmed:author |
pubmed-author:BaurStefanieS,
pubmed-author:BeilWinfriedW,
pubmed-author:ChalkouKalliopiK,
pubmed-author:FiedlerHans-PeterHP,
pubmed-author:GoodfellowMichaelM,
pubmed-author:JonesAmanda LAL,
pubmed-author:KaragouniAmalia DAD,
pubmed-author:KatsifasEfstathios AEA,
pubmed-author:MeintanisChristosC,
pubmed-author:NiehausJörgJ,
pubmed-author:SüssmuthRoderich DRD,
pubmed-author:SchneiderKathrinK,
pubmed-author:WardAlan CAC
|
pubmed:issnType |
Print
|
pubmed:volume |
59
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
293-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:16883779-Antineoplastic Agents,
pubmed-meshheading:16883779-Cell Line, Tumor,
pubmed-meshheading:16883779-Fluorenes,
pubmed-meshheading:16883779-Humans,
pubmed-meshheading:16883779-Molecular Structure,
pubmed-meshheading:16883779-Spectrometry, Mass, Electrospray Ionization,
pubmed-meshheading:16883779-Spectrophotometry, Ultraviolet,
pubmed-meshheading:16883779-Streptomyces
|
pubmed:year |
2006
|
pubmed:articleTitle |
Fluostatins C-E, novel members of the fluostatin family produced by Streptomyces strain Acta 1383.
|
pubmed:affiliation |
Mikrobiologisches Institut, Universität Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|