rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2006-8-2
|
pubmed:abstractText |
Idiopathic pulmonary fibrosis (IPF) is characterized by an uncontrolled accumulation and activation of lung fibroblasts. A modulation of fibroblast activation has been observed in various systems with octreotide, a synthetic somatostatin analog with strong affinity for the somatostatin receptor subtype 2 (sst2). One aim of our study was to evaluate the expression of somatostatin receptors in the lungs of patients with IPF. A second aim was to evaluate the relationship between 111In-octreotide uptake and the effect of pulmonary fibrosis as assessed by lung function tests and parameters and by radiologic findings.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0161-5505
|
pubmed:author |
pubmed-author:BraunerMichelM,
pubmed-author:CrestaniBrunoB,
pubmed-author:DebrayMarie-PierreMP,
pubmed-author:Gruaz-GuyonAnneA,
pubmed-author:Le GuludecDominiqueD,
pubmed-author:LebtahiRachidaR,
pubmed-author:MarchalJoëlleJ,
pubmed-author:Marchand-AdamSylvainS,
pubmed-author:MoreauSeverineS,
pubmed-author:RaguinOlivierO,
pubmed-author:ReubiJean-ClaudeJC,
pubmed-author:SolerPaulP
|
pubmed:issnType |
Print
|
pubmed:volume |
47
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1281-7
|
pubmed:meshHeading |
pubmed-meshheading:16883006-Adult,
pubmed-meshheading:16883006-Aged,
pubmed-meshheading:16883006-Antineoplastic Agents, Hormonal,
pubmed-meshheading:16883006-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:16883006-Cells, Cultured,
pubmed-meshheading:16883006-Female,
pubmed-meshheading:16883006-Fibroblasts,
pubmed-meshheading:16883006-Humans,
pubmed-meshheading:16883006-Indium Radioisotopes,
pubmed-meshheading:16883006-Lung,
pubmed-meshheading:16883006-Male,
pubmed-meshheading:16883006-Middle Aged,
pubmed-meshheading:16883006-Octreotide,
pubmed-meshheading:16883006-Pulmonary Fibrosis,
pubmed-meshheading:16883006-Receptors, Somatostatin
|
pubmed:year |
2006
|
pubmed:articleTitle |
Increased uptake of 111In-octreotide in idiopathic pulmonary fibrosis.
|
pubmed:affiliation |
Department of Nuclear Medicine, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris, France. rachida.lebtahi@bch.aphp.fr
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|