| pubmed-article:16880399 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16880399 | lifeskim:mentions | umls-concept:C0521026 | lld:lifeskim |
| pubmed-article:16880399 | lifeskim:mentions | umls-concept:C0032098 | lld:lifeskim |
| pubmed-article:16880399 | lifeskim:mentions | umls-concept:C0004896 | lld:lifeskim |
| pubmed-article:16880399 | lifeskim:mentions | umls-concept:C0015576 | lld:lifeskim |
| pubmed-article:16880399 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:16880399 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:16880399 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
| pubmed-article:16880399 | lifeskim:mentions | umls-concept:C0205214 | lld:lifeskim |
| pubmed-article:16880399 | pubmed:issue | 32 | lld:pubmed |
| pubmed-article:16880399 | pubmed:dateCreated | 2006-8-9 | lld:pubmed |
| pubmed-article:16880399 | pubmed:abstractText | Genes involved in a viral resistance response in common bean (Phaseolus vulgaris cv. Othello) were identified by inoculating a geminivirus reporter (Bean dwarf mosaic virus expressing the green fluorescent protein), extracting RNA from tissue undergoing the defense response, and amplifying sequences with degenerate R gene primers. One such gene (a TIR-NBS-LRR gene, RT4-4) was selected for functional analysis in which transgenic Nicotiana benthamiana were generated and screened for resistance to a range of viruses. This analysis revealed that RT4-4 did not confer resistance to the reporter geminivirus; however, it did activate a resistance-related response (systemic necrosis) to seven strains of Cucumber mosaic virus (CMV) from pepper or tomato, but not to a CMV strain from common bean. Of these eight CMV strains, only the strain from common bean systemically infected common bean cv. Othello. Additional evidence that RT4-4 is a CMV R gene came from the detection of resistance response markers in CMV-challenged leaves of RT4-4 transgenic plants, and the identification of the CMV 2a gene product as the elicitor of the necrosis response. These findings indicate that RT4-4 functions across two plant families and is up-regulated in a non-virus-specific manner. This experimental approach holds promise for providing insights into the mechanisms by which plants activate resistance responses against pathogens. | lld:pubmed |
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| pubmed-article:16880399 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16880399 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16880399 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16880399 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16880399 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16880399 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16880399 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:16880399 | pubmed:author | pubmed-author:LeeJung-YounJ... | lld:pubmed |
| pubmed-article:16880399 | pubmed:author | pubmed-author:LucasWilliam... | lld:pubmed |
| pubmed-article:16880399 | pubmed:author | pubmed-author:RonaldPamelaP | lld:pubmed |
| pubmed-article:16880399 | pubmed:author | pubmed-author:LeeSang-WonSW | lld:pubmed |
| pubmed-article:16880399 | pubmed:author | pubmed-author:RojasMaria... | lld:pubmed |
| pubmed-article:16880399 | pubmed:author | pubmed-author:JeonJong-Seon... | lld:pubmed |
| pubmed-article:16880399 | pubmed:author | pubmed-author:GilbertsonRob... | lld:pubmed |
| pubmed-article:16880399 | pubmed:author | pubmed-author:SeoYoung-SuYS | lld:pubmed |
| pubmed-article:16880399 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16880399 | pubmed:day | 8 | lld:pubmed |
| pubmed-article:16880399 | pubmed:volume | 103 | lld:pubmed |
| pubmed-article:16880399 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16880399 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16880399 | pubmed:pagination | 11856-61 | lld:pubmed |
| pubmed-article:16880399 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:16880399 | pubmed:meshHeading | pubmed-meshheading:16880399... | lld:pubmed |
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| pubmed-article:16880399 | pubmed:meshHeading | pubmed-meshheading:16880399... | lld:pubmed |
| pubmed-article:16880399 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16880399 | pubmed:articleTitle | A viral resistance gene from common bean functions across plant families and is up-regulated in a non-virus-specific manner. | lld:pubmed |
| pubmed-article:16880399 | pubmed:affiliation | Department of Plant Pathology and Section of Plant Biology, University of California, Davis, CA 95616, USA. | lld:pubmed |
| pubmed-article:16880399 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16880399 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16880399 | lld:pubmed |
