Linked Life Data

16870402

Source:http://linkedlifedata.com/resource/pubmed/id/16870402

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-8-22
pubmed:abstractText
We describe in this paper an approach to synthesize superparamagnetic iron oxide nanoparticles in the presence of polymerized lactic acid. The resulted particles consisted of clusters of iron oxide monocrystals, embedded inside the polymer chains. The composite particles synthesized in situ were highly dispersible in aqueous solution with good stability. X-ray diffraction and magnetometer data all confirmed the crystalline structure and super-paramagnetic property of the particles. They exhibited narrow size distribution with hydrodynamic diameters close to 80 nm. In addition, the particles were shown to have abundant surface carboxyl groups, which can be used to conjugate various biomolecules. Such a preparation would be especially useful for developing target specific MRI contrast agents or drug delivery vehicles.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0927-7765
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
101-6
pubmed:dateRevised
2009-10-16
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Synthesis and characterization of iron oxide/polymer composite nanoparticles with pendent functional groups.
pubmed:affiliation
Department of Biomedical Engineering, College of Life Science and Biotechnology, Shanghai Jiao Tong University, 1954 Hua-Shan Road, Shanghai 200030, PR China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't