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pubmed-article:16864486pubmed:abstractTextThe lipopolysaccharide (LPS)-induced chinchilla otitis media (OM) model was proven useful in screening anti-inflammatory agents for topical use. Both 1% rimexolone and 1% dexamethasone are effective in reducing the volume of middle ear effusion and mucosal thickness compared with control groups. Topical corticosteroid therapy was efficacious in reducing middle ear mucosal inflammation.lld:pubmed
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pubmed-article:16864486pubmed:articleTitleEffect of topical dexamethasone versus rimexolone on middle ear inflammation in experimental otitis media with effusion.lld:pubmed
pubmed-article:16864486pubmed:affiliationDivision of Otolaryngology-Head & Neck Surgery, Loma Linda University School of Medicine, Loma Linda, CA, USA.lld:pubmed
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pubmed-article:16864486pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed