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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-7-25
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pubmed:abstractText |
The lipopolysaccharide (LPS)-induced chinchilla otitis media (OM) model was proven useful in screening anti-inflammatory agents for topical use. Both 1% rimexolone and 1% dexamethasone are effective in reducing the volume of middle ear effusion and mucosal thickness compared with control groups. Topical corticosteroid therapy was efficacious in reducing middle ear mucosal inflammation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0001-6489
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pubmed:author |
pubmed-author:DepewAronA,
pubmed-author:FloreaAndrewA,
pubmed-author:InmanJaredJ,
pubmed-author:JohnEarnestE,
pubmed-author:JohnsonKaalanK,
pubmed-author:JungTimothyT,
pubmed-author:LeeChoong-WonCW,
pubmed-author:ParkSeong KookSK,
pubmed-author:WallG MichaelGM,
pubmed-author:WarehamRachelleR,
pubmed-author:ZwartJon EJE
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pubmed:issnType |
Print
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pubmed:volume |
126
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
910-5
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pubmed:meshHeading |
pubmed-meshheading:16864486-Administration, Topical,
pubmed-meshheading:16864486-Animals,
pubmed-meshheading:16864486-Chinchilla,
pubmed-meshheading:16864486-Dexamethasone,
pubmed-meshheading:16864486-Disease Models, Animal,
pubmed-meshheading:16864486-Female,
pubmed-meshheading:16864486-Glucocorticoids,
pubmed-meshheading:16864486-Male,
pubmed-meshheading:16864486-Microscopy,
pubmed-meshheading:16864486-Mucous Membrane,
pubmed-meshheading:16864486-Otitis Media with Effusion,
pubmed-meshheading:16864486-Periosteum,
pubmed-meshheading:16864486-Pregnadienes,
pubmed-meshheading:16864486-Random Allocation,
pubmed-meshheading:16864486-Temporal Bone
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pubmed:year |
2006
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pubmed:articleTitle |
Effect of topical dexamethasone versus rimexolone on middle ear inflammation in experimental otitis media with effusion.
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pubmed:affiliation |
Division of Otolaryngology-Head & Neck Surgery, Loma Linda University School of Medicine, Loma Linda, CA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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