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pubmed-article:16863919pubmed:abstractTextPertussis toxin (PT) has the capacity to activate dendritic cells (DCs) for the augmentation of cell-mediated immune responses. To investigate the mechanism(s) by which PT activates DCs, we investigated the effects of PT and its B-oligomer (PTB) on the maturation of human and mouse DCs and determined whether PT could act as a pathogen-associated molecular pattern to activate one of the Toll-like receptors (TLRs).lld:pubmed
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pubmed-article:16863919pubmed:articleTitleInduction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.lld:pubmed
pubmed-article:16863919pubmed:affiliationIntramural Basic Research Program, SAIC-Frederick, Inc, USA.lld:pubmed
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