Source:http://linkedlifedata.com/resource/pubmed/id/16863919
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2006-7-25
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pubmed:abstractText |
Pertussis toxin (PT) has the capacity to activate dendritic cells (DCs) for the augmentation of cell-mediated immune responses. To investigate the mechanism(s) by which PT activates DCs, we investigated the effects of PT and its B-oligomer (PTB) on the maturation of human and mouse DCs and determined whether PT could act as a pathogen-associated molecular pattern to activate one of the Toll-like receptors (TLRs).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0301-472X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1115-24
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16863919-Animals,
pubmed-meshheading:16863919-Dendritic Cells,
pubmed-meshheading:16863919-Female,
pubmed-meshheading:16863919-Humans,
pubmed-meshheading:16863919-Lymphocyte Activation,
pubmed-meshheading:16863919-Mice,
pubmed-meshheading:16863919-Mice, Inbred C3H,
pubmed-meshheading:16863919-Pertussis Toxin,
pubmed-meshheading:16863919-Protein Subunits,
pubmed-meshheading:16863919-Signal Transduction,
pubmed-meshheading:16863919-Toll-Like Receptor 4,
pubmed-meshheading:16863919-Transfection
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pubmed:year |
2006
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pubmed:articleTitle |
Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.
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pubmed:affiliation |
Intramural Basic Research Program, SAIC-Frederick, Inc, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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