Source:http://linkedlifedata.com/resource/pubmed/id/16860321
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
18
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pubmed:dateCreated |
2006-8-1
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pubmed:abstractText |
A large DNA virus, designated koi herpes virus (KHV), carp interstitial nephritis gill necrosis virus (CNGV) and Cyprinid herpes virus-3 (CyHV-3), causes massive mortality of carp. Morphologically, the virus resembles herpes viruses, but it contains a genome of ca 295 kbp, larger than that of any Herpesviridae member. Interestingly, three CyHV-3 genes, thymidylate monophosphate kinase (TmpK), ribonucleotide reductase and thymidine kinase, which are involved in deoxynucleotide tri-phosphate synthesis, resemble those of pox viruses. In addition to the TmpK gene, which is nonexistent in the genome of herpes viruses, CyHV-3 contains a B22R-like gene, exclusively expressed by pox viruses. These results raise questions on the phylogenic origin of CyHV-3.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
580
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4473-8
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pubmed:meshHeading |
pubmed-meshheading:16860321-Amino Acid Sequence,
pubmed-meshheading:16860321-Animals,
pubmed-meshheading:16860321-Carps,
pubmed-meshheading:16860321-Cell Line,
pubmed-meshheading:16860321-Genes, Viral,
pubmed-meshheading:16860321-Genome, Viral,
pubmed-meshheading:16860321-Herpesviridae,
pubmed-meshheading:16860321-Molecular Sequence Data,
pubmed-meshheading:16860321-Phylogeny,
pubmed-meshheading:16860321-Poxviridae,
pubmed-meshheading:16860321-Sequence Alignment,
pubmed-meshheading:16860321-Viral Proteins
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pubmed:year |
2006
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pubmed:articleTitle |
Cyprinid herpes virus-3 (CyHV-3) bears genes of genetically distant large DNA viruses.
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pubmed:affiliation |
Department of Pathology, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
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pubmed:publicationType |
Journal Article
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