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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2006-7-24
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pubmed:abstractText |
Patients undergoing enucleation and adjuvant interferon therapy for giant cell jaw tumors have been observed to exhibit exuberant bone formation in the resultant defects. We hypothesize that interferon promotes bone formation by enhancing mesenchymal stem cell (MSC) differentiation and by stimulating osteoblasts. This is a preliminary study to determine the effects of interferon on porcine mesenchymal stem cells (pMSCs) in culture.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0278-2391
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1214-20
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16860212-Alkaline Phosphatase,
pubmed-meshheading:16860212-Animals,
pubmed-meshheading:16860212-Cell Differentiation,
pubmed-meshheading:16860212-Cell Proliferation,
pubmed-meshheading:16860212-Cells, Cultured,
pubmed-meshheading:16860212-DNA,
pubmed-meshheading:16860212-Female,
pubmed-meshheading:16860212-Humans,
pubmed-meshheading:16860212-Interferon-alpha,
pubmed-meshheading:16860212-Mesenchymal Stem Cells,
pubmed-meshheading:16860212-Osteoblasts,
pubmed-meshheading:16860212-Osteogenesis,
pubmed-meshheading:16860212-Recombinant Proteins,
pubmed-meshheading:16860212-Swine,
pubmed-meshheading:16860212-Swine, Miniature
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pubmed:year |
2006
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pubmed:articleTitle |
Effect of interferon-alpha-2b on porcine mesenchymal stem cells.
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pubmed:affiliation |
Skeletal Biology Research Center, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital and Harvard School of Dental Medicine, Boston, MA 02114, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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