Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1975-11-8
pubmed:abstractText
Cell cultures prepared from fetal murine liver were infected by Abelson murine leukemia virus. After about 2 weeks, proliferating cells of lymphoid morphology appeared in some of the cultures. Addition of 2-mercaptoethanol to the initial culture medium greatly enhanced the appearance of the lymphoid cells. Immunoglobulin determinants were evident on the cells in some cultures. Continuous passage of the cells in certain cultures was possible and the passaged cells could form tumors after animal inoculation. Because Abelson murine leukemia virus is able to induce in vitro malignant transformation of lymphoid cells, it probably causes leukemia by directly affecting cellular growth control.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-13864532, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-14010247, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-163444, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-163975, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4099080, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4112916, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4200776, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4300361, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4318922, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4318985, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4333982, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4347027, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4354852, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4355680, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4368895, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4372605, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4551488, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4604328, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4672864, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4727914, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-4831439, http://linkedlifedata.com/resource/pubmed/commentcorrection/168584-5223941
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1932-6
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
In vitro transformation of lymphoid cells by Abelson murine leukemia virus.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.