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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1992-3-10
|
| pubmed:abstractText |
To characterize further the nature of haemostatic impairment in haemorrhagic fever with renal syndrome, we assessed platelet function in 9 patients in whom the diagnosis was serologically confirmed. Defective platelet aggregation was demonstrated in every patient. An abnormality of the granule release reaction was demonstrated in all of 7 patients tested. Gel-filtered platelets from a normal subject showed normal aggregation in plasma from a patient with impaired aggregation, which is evidence for an intrinsic platelet defect, and against the presence of a circulating inhibitor in this patient.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0035-9203
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
85
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
660-3
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:1685813-Adenosine Diphosphate,
pubmed-meshheading:1685813-Adult,
pubmed-meshheading:1685813-Blood Platelets,
pubmed-meshheading:1685813-Cytoplasmic Granules,
pubmed-meshheading:1685813-Hemorrhagic Fever with Renal Syndrome,
pubmed-meshheading:1685813-Humans,
pubmed-meshheading:1685813-Male,
pubmed-meshheading:1685813-Platelet Aggregation
|
| pubmed:articleTitle |
Platelet dysfunction contributes to the haemostatic defect in haemorrhagic fever with renal syndrome.
|
| pubmed:affiliation |
Medical Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland.
|
| pubmed:publicationType |
Journal Article
|