|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0016004,
umls-concept:C0025932,
umls-concept:C0026336,
umls-concept:C0030279,
umls-concept:C0034897,
umls-concept:C0045093,
umls-concept:C0205276,
umls-concept:C0205430,
umls-concept:C0346647,
umls-concept:C0679199,
umls-concept:C1280500,
umls-concept:C1708528
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|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2006-7-21
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|
pubmed:abstractText |
Pancreatic cancer frequently recurs after operative treatment, resulting in a poor prognosis. Inhibition of proliferation of residual cancer cells is important for improved survival of patients with pancreatic cancer. Fibrin glue (FG) is a biocompatible, adherent hemostat that can deliver high concentrations of anticancer drugs to residual cancer cells. The aim of this study was to evaluate the local antitumor effect of a mixture of gemcitabine (GEM) and FG on pancreatic cancer cells implanted orthotopically in nude mice.
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pubmed:language |
eng
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|
pubmed:journal |
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|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0039-6060
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
140
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
66-71
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|
pubmed:meshHeading |
pubmed-meshheading:16857444-Animals,
pubmed-meshheading:16857444-Antineoplastic Agents,
pubmed-meshheading:16857444-Cell Line, Tumor,
pubmed-meshheading:16857444-Combined Modality Therapy,
pubmed-meshheading:16857444-Deoxycytidine,
pubmed-meshheading:16857444-Fibrin Tissue Adhesive,
pubmed-meshheading:16857444-Fluorescent Dyes,
pubmed-meshheading:16857444-Humans,
pubmed-meshheading:16857444-Mice,
pubmed-meshheading:16857444-Mice, Nude,
pubmed-meshheading:16857444-Neoplasm Recurrence, Local,
pubmed-meshheading:16857444-Neoplasm Transplantation,
pubmed-meshheading:16857444-Pancreatectomy,
pubmed-meshheading:16857444-Pancreatic Neoplasms,
pubmed-meshheading:16857444-Rhodamines,
pubmed-meshheading:16857444-Transplantation, Heterologous
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|
pubmed:year |
2006
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|
pubmed:articleTitle |
Strategy for prevention of local recurrence of pancreatic cancer after pancreatectomy: antitumor effect of gemcitabine mixed with fibrin glue in an orthotopic nude mouse model.
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pubmed:affiliation |
Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article
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