|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2006-11-20
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|
pubmed:abstractText |
We identified the BRK tyrosine kinase in a PCR-based screen of tyrosine kinases expressed by ovarian tumors. BRK expression is restricted to normal differentiating epithelial cells and its overexpression may play a role in processes related to tumor development and growth. Its expression in normal ovary and ovarian tumors has not previously been described, and is the focus of this study.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1538-4047
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
5
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1136-41
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|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:16855388-Cell Line, Tumor,
pubmed-meshheading:16855388-Cloning, Molecular,
pubmed-meshheading:16855388-Cystadenocarcinoma, Serous,
pubmed-meshheading:16855388-Female,
pubmed-meshheading:16855388-Gene Amplification,
pubmed-meshheading:16855388-Humans,
pubmed-meshheading:16855388-Immunohistochemistry,
pubmed-meshheading:16855388-In Situ Hybridization, Fluorescence,
pubmed-meshheading:16855388-Neoplasm Proteins,
pubmed-meshheading:16855388-Ovarian Neoplasms,
pubmed-meshheading:16855388-Protein-Tyrosine Kinases
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
The BRK tyrosine kinase is expressed in high-grade serous carcinoma of the ovary.
|
|
pubmed:affiliation |
Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230-1439, USA. rschmand@mdanderson.org
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
