Linked Life Data

16851397

Source:http://linkedlifedata.com/resource/pubmed/id/16851397

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2006-7-20
pubmed:abstractText
Boltzmann-like distributions appear in many properties and energy-related quantities of proteins. A few examples are hydrophobicity, various types of side-chain/side-chain interactions, proline isomerization, hydrogen bonds, internal cavities, interactions at the level of specific atom types, and the propensity of the phi/'phi' ratio. Here, we conjecture that the Boltzmann hypothesis also holds for the intra-residue energy distribution. We confirm the conjecture by calculating the energies of 41,672 residues of the structures of highly resolved proteins, where at least 12 out of 20 naturally occurring amino acids follow Boltzmann's law. We further examine the entire set of all residue energies and find that the convolution of the individual distributions gives a Poisson function, which is followed by approximately 50% of individual proteins' structures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1520-6106
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
109
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3586-93
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Intraresidue distribution of energy in proteins.
pubmed:affiliation
Dipartimento di Chimica "G. Ciamician" and Dipartimento di Biologia, Università di Bologna, via F. Selmi 2, 40126 Bologna, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't