|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1992-2-11
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|
pubmed:abstractText |
Five beta-adrenergic blocking agents and two alpha-sympathicomimetics were separated after derivatization with (R)-(-)-1-(Naphth-1-yl)-ethylisocyanate (NEIC). For two of these analytes the separation was successful also after reaction with (R)-(+)-1-phenylethylisocyanate (PEIC) by using HPLC with RP-18 phases and a water-methanolic eluent by UV-detection on 254 nm. After reaction with (1S)-(+)-campher-10-sulfonylchloride (CSC) an acceptable separation of norphenylephedrine also was possible. Analytes which can be derivated with NEIC and PEIC give no reaction with CSC (and vice versa).
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pubmed:language |
ger
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0031-7144
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
46
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
432-4
|
|
pubmed:dateRevised |
2007-1-29
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|
pubmed:meshHeading |
|
|
pubmed:year |
1991
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|
pubmed:articleTitle |
[The separation of some racemic beta-blockers and alpha-sympathomimetics with HPLC following derivatization].
|
|
pubmed:affiliation |
Fachbereich Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.
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|
pubmed:publicationType |
Journal Article,
English Abstract
|
