Source:http://linkedlifedata.com/resource/pubmed/id/16846604
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2007-4-24
|
| pubmed:abstractText |
The complement system is activated in human atherosclerotic lesions and may hence aggravate local inflammation. We studied the presence and localization of C4b-binding protein (C4bp), the major inhibitor of the classical complement pathway, in human atherosclerotic lesions in relation to complement activation products and protein S, which circulates in complex with C4bp.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0021-9150
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
192
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
40-8
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:16846604-Apoptosis,
pubmed-meshheading:16846604-Complement C4b-Binding Protein,
pubmed-meshheading:16846604-Complement Membrane Attack Complex,
pubmed-meshheading:16846604-Complement Pathway, Alternative,
pubmed-meshheading:16846604-Complement Pathway, Classical,
pubmed-meshheading:16846604-Coronary Artery Disease,
pubmed-meshheading:16846604-Coronary Vessels,
pubmed-meshheading:16846604-Histocytochemistry,
pubmed-meshheading:16846604-Humans,
pubmed-meshheading:16846604-Tunica Intima
|
| pubmed:year |
2007
|
| pubmed:articleTitle |
Complement regulation in human atherosclerotic coronary lesions. Immunohistochemical evidence that C4b-binding protein negatively regulates the classical complement pathway, and that C5b-9 is formed via the alternative complement pathway.
|
| pubmed:affiliation |
Wihuri Research Institute, Kalliolinnantie 4, FIN-00140 Helsinki, Finland.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|