Source:http://linkedlifedata.com/resource/pubmed/id/16845933
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2006-7-18
|
pubmed:abstractText |
Repeated saline injections induce reorganization of the circadian locomotor rhythm in rats, which is manifested by increased amplitude, enhanced instability of the acrophase, and changed spectral characteristics. The benzodiazepine anxiolytic tofisopam (grandaxin, 10 mg/kg) and the pineal hormone melatonin (0.1 mg/kg) prevented the stress-induced changes in the circadian rhythm. The hormone exhibited a more optimal chronotropic activity than grandaxin.
|
pubmed:language |
rus
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0869-2092
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
69
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
14-7
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:16845933-Animals,
pubmed-meshheading:16845933-Anti-Anxiety Agents,
pubmed-meshheading:16845933-Benzodiazepines,
pubmed-meshheading:16845933-Circadian Rhythm,
pubmed-meshheading:16845933-Drug Therapy, Combination,
pubmed-meshheading:16845933-Melatonin,
pubmed-meshheading:16845933-Motor Activity,
pubmed-meshheading:16845933-Rats,
pubmed-meshheading:16845933-Rats, Inbred Strains,
pubmed-meshheading:16845933-Stress, Physiological
|
pubmed:articleTitle |
[Tofisopam and melatonin attenuate the reorganization of circadian locomotor rhythm in rats under injection-induced stress conditions].
|
pubmed:publicationType |
Journal Article,
English Abstract
|