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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-9-4
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pubmed:abstractText |
A second vesicular glutamate transporter (VGLUT2) is detected in magnocellular neurons in the rat hypothalamus. The present study revealed what phenotype of neurons express VGLUT2 mRNA by the histological method. We found that most vasopressin (VP) neurons and several oxytocin (OT) neurons express VGLUT2 mRNA. VGLUT2 gene expression in VP and OT neurons is enhanced with osmotic challenges. In the neurohypophysis, VGLUT2-staining in OT terminals was reduced with osmotic stimulation. These results indicate that VGLUT2 is principally expressed in VP neurons and also in some OT neurons and that VGLUT2 in VP and OT neurons is involved in osmotic regulation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0168-0102
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
124-7
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pubmed:meshHeading |
pubmed-meshheading:16842872-Animals,
pubmed-meshheading:16842872-Cell Shape,
pubmed-meshheading:16842872-Dehydration,
pubmed-meshheading:16842872-Male,
pubmed-meshheading:16842872-Neurons,
pubmed-meshheading:16842872-Osmolar Concentration,
pubmed-meshheading:16842872-Oxytocin,
pubmed-meshheading:16842872-Paraventricular Hypothalamic Nucleus,
pubmed-meshheading:16842872-Rats,
pubmed-meshheading:16842872-Rats, Sprague-Dawley,
pubmed-meshheading:16842872-Salts,
pubmed-meshheading:16842872-Supraoptic Nucleus,
pubmed-meshheading:16842872-Up-Regulation,
pubmed-meshheading:16842872-Vasopressins,
pubmed-meshheading:16842872-Vesicular Glutamate Transport Protein 2,
pubmed-meshheading:16842872-Water Deprivation
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pubmed:year |
2006
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pubmed:articleTitle |
VGLUT2 expression is up-regulated in neurohypophysial vasopressin neurons of the rat after osmotic stimulation.
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pubmed:affiliation |
Laboratory of Neuroendocrinology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan. a-kawasaki@gakuen-hospital.or.jp
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pubmed:publicationType |
Journal Article
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