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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-12-4
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pubmed:abstractText |
Expression of RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) is associated with prognosis of various malignancies including uterine cancer. Proteolytic cleavage of RCAS1 at extracellular domains (ectodomain shedding) yields soluble RCAS1. Although RCAS1 can induce apoptosis in normal peripheral lymphocytes, its biologic function in cancer patients is unclear. Here, we evaluated serum RCAS1 concentrations to clarify its biologic activity in uterine cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0090-8258
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
924-31
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pubmed:meshHeading |
pubmed-meshheading:16842844-Adenocarcinoma,
pubmed-meshheading:16842844-Adenocarcinoma, Clear Cell,
pubmed-meshheading:16842844-Antigens, Neoplasm,
pubmed-meshheading:16842844-Biological Markers,
pubmed-meshheading:16842844-Carcinoma, Endometrioid,
pubmed-meshheading:16842844-Carcinoma, Squamous Cell,
pubmed-meshheading:16842844-Case-Control Studies,
pubmed-meshheading:16842844-Cystadenocarcinoma, Serous,
pubmed-meshheading:16842844-Endometrial Neoplasms,
pubmed-meshheading:16842844-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16842844-Female,
pubmed-meshheading:16842844-Humans,
pubmed-meshheading:16842844-Middle Aged,
pubmed-meshheading:16842844-Neoplasm Staging,
pubmed-meshheading:16842844-Predictive Value of Tests,
pubmed-meshheading:16842844-Uterine Cervical Neoplasms
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pubmed:year |
2006
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pubmed:articleTitle |
Clinical significance of RCAS1 as a biomarker of uterine cancer.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. kenzo@gynob.med.kyushu-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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