Linked Life Data

16841307

Source:http://linkedlifedata.com/resource/pubmed/id/16841307

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-7-20
pubmed:abstractText
Zinc pyrithione (ZnPT) or copper pyrithione (CuPT) have been effectively used as ship-antifouling agents, as an alternative to organotin compounds. Because of their instability in light and a lack of suitable analytical procedures, there is little data on their residue levels in environmental matrices. It is possible to investigate the fate of such compounds by toxicity alteration with certain treatments. The purpose of this study was to evaluate the degradation of pyrithiones through toxicity reduction by near ultraviolet (UV-A) irradiation. Metal pyrithiones dissolved in acetonitrile were irradiated with a UV-A lamp for 0, 0.5, 1, and 2 h, and were subjected to UV spectral measurement and toxicity evaluation using both sea urchin and freshwater rotifer bioassays. For the bioassays, photolyzed samples were dissolved in dimethyl sulfoxide after evaporation of the acetonitrile. The changes in UV spectra of photolyzed ZnPT or CuPT showed a time-dependent degradation, and the UV spectra at 2 h irradiation suggested substantial decomposition. Toxicities of ZnPT and CuPT were 12 and 5 microg/L as 24 h LC50 to the survival of rotifers and 10(-6) ng/L and 2.3 ng/L as 27 h EC50 to normal pluteus formation, respectively. By evaporation of the acetonitrile, the EC50 of ZnPT was 2.2 ng/L, which was the same as that of CuPT. The EC50s of ZnPT or CuPT for both species increased with longer irradiation times. Photolyzed ZnPT or CuPT demonstrated substantial degradation in the UV spectra, but possessed marked toxicity, which is probably due to toxic degradation products. One reason why photolyzed CuPT was toxic to rotifers was explained by the high toxicity of copper ions formed by UV-A irradiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1520-4081
pubmed:author
pubmed:copyrightInfo
Copyright 2006 Wiley Periodicals, Inc.
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
305-9
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Toxicity reduction of metal pyrithiones by near ultraviolet irradiation.
pubmed:affiliation
Laboratory of Marine Environmental Management, Faculty of Maritime Sciences, Kobe University, Fukaeminami 5-1-1 Higashinada, Kobe 658-0022, Japan. okamura@maritime.kobe-u.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't