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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2006-9-1
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pubmed:abstractText |
We report on a new electrodynamic ion funnel that operates at a pressure of 30 torr with no loss of ion transmission. The enhanced performance compared with previous ion funnel designs optimized for pressures of <5 torr was achieved by reducing the ion funnel capacitance and increasing the RF drive frequency (1.7 MHz) and amplitude (100-170 V peak-to-peak). No degradation of ion transmission was observed for pressures from 2 to 30 torr. The ability to operate at higher pressure enabled a new tandem ion funnel mass spectrometer interface design that can accommodate a greater gas load (e.g., from an ESI source). When combined with a multicapillary inlet, the interface provided more efficient introduction of ions, resulting in a significant enhancement in mass spectrometer sensitivity and detection limits.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-10450147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-10631660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-10845370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-11338576,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-11569805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-12216730,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-14528493,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-14588040,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-15096064,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-15253651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-15389859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-15734324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-15889926,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-16194076,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-2194402,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-8779426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16839773-9784749
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1044-0305
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1299-305
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pubmed:dateRevised |
2011-1-25
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pubmed:meshHeading |
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pubmed:year |
2006
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pubmed:articleTitle |
Improving mass spectrometer sensitivity using a high-pressure electrodynamic ion funnel interface.
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pubmed:affiliation |
Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Evaluation Studies
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