|
rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0004368,
umls-concept:C0024790,
umls-concept:C0035647,
umls-concept:C0035820,
umls-concept:C0040100,
umls-concept:C0205210,
umls-concept:C0242629,
umls-concept:C0332283,
umls-concept:C0449255,
umls-concept:C1710548
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pubmed:issue |
10
|
|
pubmed:dateCreated |
2006-9-14
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|
pubmed:abstractText |
Seven years after a surgically resected thymoma, a female patient affected by myasthenia gravis and Good's syndrome presented with paroxysmal nocturnal hemoglobinuria (PNH). Co-culture experiments and spectratyping analyses indicated that CD8+ lymphocytes were involved in damaging hematopoietic precursors. While PNH clones have been identified in various hematological disorders, the sequential association of thymoma and PNH has been unreported so far.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
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pubmed:issn |
0361-8609
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|
pubmed:author |
pubmed-author:BulgarelliGoffredoG,
pubmed-author:Del VecchioLuigiL,
pubmed-author:MasciAnnamariaA,
pubmed-author:MerkabaouiGhassanG,
pubmed-author:MontellaLilianaL,
pubmed-author:PalmieriGiovannellaG,
pubmed-author:RacioppiLuigiL,
pubmed-author:RicciPatriziaP,
pubmed-author:RotoliBrunoB,
pubmed-author:SelleriCarmineC,
pubmed-author:VitielloLauraL
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|
pubmed:issnType |
Print
|
|
pubmed:volume |
81
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
774-8
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|
pubmed:meshHeading |
pubmed-meshheading:16838334-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16838334-Autoimmune Diseases,
pubmed-meshheading:16838334-Autoimmunity,
pubmed-meshheading:16838334-CD8-Positive T-Lymphocytes,
pubmed-meshheading:16838334-Female,
pubmed-meshheading:16838334-Follow-Up Studies,
pubmed-meshheading:16838334-Hemoglobinuria, Paroxysmal,
pubmed-meshheading:16838334-Humans,
pubmed-meshheading:16838334-Middle Aged,
pubmed-meshheading:16838334-Neoplasm Recurrence, Local,
pubmed-meshheading:16838334-Receptors, Antigen, T-Cell, alpha-beta,
pubmed-meshheading:16838334-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16838334-Thymoma,
pubmed-meshheading:16838334-Thymus Neoplasms
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pubmed:year |
2006
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|
pubmed:articleTitle |
Thymoma followed by paroxysmal nocturnal hemoglobinuria: a unique clinical association in the context of multiorgan autoimmunity with a potential role for CD8+ T lymphocytes.
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|
pubmed:affiliation |
Department of Molecular and Clinical Endocrinology & Oncology, Federico II University, Naples, Italy. giovannella.palmieri@email.it
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pubmed:publicationType |
Journal Article,
Case Reports
|
