Linked Life Data

16837600

Source:http://linkedlifedata.com/resource/pubmed/id/16837600

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
28
pubmed:dateCreated
2006-7-13
pubmed:abstractText
Although studies in animals and patients have demonstrated that brain oscillations play a role in declarative memory encoding and retrieval, little has been done to investigate the temporal dynamics and sources of brain activity in healthy human subjects performing such tasks. In a magnetoencephalography study using pictorial stimuli, we have now identified oscillatory activity in the gamma (60-90 Hz) and theta (4.5-8.5 Hz) band during declarative memory operations in healthy participants. Both theta and gamma activity was stronger for the later remembered compared with the later forgotten items (the "subsequent memory effect"). In the retrieval session, theta and gamma activity was stronger for recognized items compared with correctly rejected new items (the "old/new effect"). The gamma activity was also stronger for recognized compared with forgotten old items (the "recognition effect"). The effects in the theta band were observed over right parietotemporal areas, whereas the sources of the effects in the gamma band were identified in Brodmann area 18/19. We propose that the theta activity is directly engaged in mnemonic operations. The increase in neuronal synchronization in the gamma band in occipital areas may result in a stronger drive to subsequent areas, thus facilitating both memory encoding and retrieval. Alternatively, the gamma synchronization might reflect representations being reinforced by top-down activity from higher-level memory areas. Our results provide additional insight on human declarative memory operations and oscillatory brain activity that complements previous electrophysiological and brain imaging studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1529-2401
pubmed:author
pubmed:issnType
Electronic
pubmed:day
12
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7523-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Theta and gamma oscillations predict encoding and retrieval of declarative memory.
pubmed:affiliation
F. C. Donders Center for Cognitive Neuroimaging, 6500 HB Nijmegen, The Netherlands. daria.osipova@fcdonders.ru.nl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't