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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-7-13
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pubmed:abstractText |
Allergic asthma is thought to be mediated by CD4+ T lymphocytes producing the Th2-associated cytokines, which play a critical role in the development of the airway hyper-responsiveness and the eosinophilic inflammatory response. The costimulatory pathway CD28/B7 has been shown to play an important role in CD4+ T cell activation in allergic asthma. This study was conducted to evaluate the role of another costimulatory pathway OX40/OX40 ligand (L) in the pathogenesis of allergic asthma in BALB/c mice.
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pubmed:language |
chi
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-4,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/OX40Ig,
http://linkedlifedata.com/resource/pubmed/chemical/Ovalbumin,
http://linkedlifedata.com/resource/pubmed/chemical/Tnfsf4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0578-1310
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
455-8
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pubmed:meshHeading |
pubmed-meshheading:16836859-Animals,
pubmed-meshheading:16836859-Antibodies, Monoclonal,
pubmed-meshheading:16836859-Antigens, Differentiation,
pubmed-meshheading:16836859-Asthma,
pubmed-meshheading:16836859-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:16836859-Disease Models, Animal,
pubmed-meshheading:16836859-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16836859-Eosinophils,
pubmed-meshheading:16836859-Female,
pubmed-meshheading:16836859-Immunoglobulin G,
pubmed-meshheading:16836859-Immunohistochemistry,
pubmed-meshheading:16836859-Interferon-gamma,
pubmed-meshheading:16836859-Interleukin-4,
pubmed-meshheading:16836859-Leukocyte Count,
pubmed-meshheading:16836859-Leukocytes,
pubmed-meshheading:16836859-Lung,
pubmed-meshheading:16836859-Lymphocytes,
pubmed-meshheading:16836859-Membrane Glycoproteins,
pubmed-meshheading:16836859-Mice,
pubmed-meshheading:16836859-Mice, Inbred BALB C,
pubmed-meshheading:16836859-Ovalbumin,
pubmed-meshheading:16836859-Tumor Necrosis Factors
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pubmed:year |
2006
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pubmed:articleTitle |
[Effects of costimulatory pathway OX40/OX40L on the pathogenesis of allergic asthma in mice].
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pubmed:affiliation |
Department of Pulmonology, Children's Hospital, Soochow University, Suzhou 215003, China.
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pubmed:publicationType |
Journal Article,
English Abstract
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