Linked Life Data

16833139

Source:http://linkedlifedata.com/resource/pubmed/id/16833139

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2006-7-12
pubmed:abstractText
Despite the fact that marine fish contain relatively high concentrations of the naturally occurring arsenic compound arsenobetaine, little is known about the disposition of arsenobetaine in fish. We investigated the accumulation, distribution, and elimination of dietary arsenobetaine in Atlantic salmon (Salmo salar L.) and Atlantic cod (Gadus morhua L.), with the focus on muscle, liver, and kidney tissues. The fish were exposed to dietary arsenobetaine (24.7 +/- 0.6 microg As/g feed) for three months, followed by a three-month depuration period. The two species showed marked differences in the accumulation and elimination of arsenobetaine. Total arsenic concentrations in Atlantic salmon increased significantly in muscle, liver, and kidney, whereas in Atlantic cod, a significant increase in total arsenic concentration was observed only in muscle. Elimination kinetics in muscle were distinct between the two species, with elimination half-lives from muscle tissue estimated at approximately 77 d in Atlantic cod and 37 d in Atlantic salmon, resulting in an absorption efficiency approximately twofold higher in Atlantic cod (15 +/- 1%) compared to that in Atlantic salmon (8 +/- 1%). The differences in arsenobetaine disposition studied in Atlantic salmon and Atlantic cod contribute to explain the differences in arsenic levels observed among marine fish.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0730-7268
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1787-94
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Accumulation and elimination of dietary arsenobetaine in two species of fish, Atlantic salmon (Salmo salar L.) and Atlantic cod (Gadus morhua L.).
pubmed:affiliation
National Institute of Nutrition and Seafood Research, P.O. Box 2029 Nordnes, 5817 Bergen, Norway. heidi.amlund@nifes.no
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't